GMP grade Cagrilintide API for Isitofu
| Igama leGeneric: | Cagrilintide |
| Inombolo yeCas: | 1415456-99-3 |
| Ifomula yemolekyuli: | I-C194H312N54O59S2 |
| Ubunzima bemolekyuli: | 4109 g/mol |
| Imbonakalo: | Umgubo omhlophe |
| Isicelo: | I-Cagrilintide liyeza elisetyenziselwa ukunyanga isifo seswekile se-2.Yi-peptide yokwenziwa esebenza njenge-agonist kwi-glucagon-like peptide-1 (GLP-1) receptor.I-GLP-1 yihomoni eveliswa emathunjini enceda ukulawula amanqanaba eswekile yegazi.I-Caglilin peptides isebenza ngokuvuselela i-GLP-1 receptor, ekhokelela ekwandeni kwe-insulin secretion, ukuncipha kwe-glucagon secretion, kunye nokukhupha isisu esicothayo.Oku ekugqibeleni kunceda ukulawula amanqanaba eswekile yegazi kubantu abanesifo sikashukela sohlobo lwe-2. Ukongeza kwimiphumo yayo kwi-insulin kunye ne-glucagon secretion, i-caglilintide ineminye imiphumo emihle kunyango lwe-2 yeswekile.Kufunyenwe ukukhuthaza ukuvakalelwa kokuzala, okubangela ukunciphisa ukutya kunye nokulahlekelwa kwesisindo kwezinye izigulane.Oku kubalulekile kuba ukulahleka kwesisindo kuhambelana nokulawulwa kwe-glycemic ephuculweyo kunye nokunciphisa umngcipheko weengxaki zenhliziyo kubantu abanesifo sikashukela sohlobo lwe-2.Ukongezelela, i-canagrelin tide ibonakaliswe ukuba ineenzuzo zenhliziyo.Kufunyenwe ukuphucula umsebenzi wentliziyo kunye nokunciphisa ukuvuvukala kwi-cardiovascular system, ingxaki eqhelekileyo kubantu abanesifo sikashukela.Oku kwenza kube lukhetho oluxabisekileyo kwizigulane ezineswekile kunye nesifo senhliziyo.I-Canagrelin idla ngokutofwa ngaphantsi kwesikhumba kanye okanye kabini yonke imihla.Kubalulekile ukuba izigulane zifumane imfundo efanelekileyo kunye nesikhokelo malunga nendlela yokuzisebenzisa ngokwazo amayeza ukuqinisekisa ukusetyenziswa okusebenzayo nokukhuselekileyo.Njengalo naliphi na iyeza, i-caglilintide ineziphumo ebezingalindelekanga.Ezona ziphumo bezingalindelekanga ziquka isicaphucaphu, ukugabha kunye norhudo.Ezi ziphumo bezingalindelekanga zihlala ziphucuka ngokuhamba kwexesha njengoko umzimba ulungelelanisa amayeza.I-Canagrelin inokunyusa umngcipheko we-hypoglycemia, ngakumbi xa isetyenziswe kunye nezinye ii-antidiabetic agents.Ukuhlolwa rhoqo amanqanaba eswekile yegazi kuyimfuneko ukuthintela kunye nokulawula i-hypoglycemia.Ngokubanzi, i-caglilin tide yongezwa okubalulekileyo kwiinketho zonyango lwezigulane ezinesifo seswekile se-2.Inceda ukulawula amanqanaba eswekile yegazi, ikhuthaza ukunciphisa umzimba, kwaye ineenzuzo zentliziyo.Nangona kunjalo, kubalulekile ukuba izigulana zisebenze ngokusondeleyo kunye nomboneleli wabo wezempilo ukugqiba ukuba i-canagrelintide lukhetho olufanelekileyo kubo kunye nokuqinisekisa ukuba ichiza lisetyenziswa ngokukhuselekileyo nangempumelelo. |
| Umqulu: | ibhegi yefoyile ye-aluminiyam okanye i-TIN ye-aluminium okanye ngokweemfuno zomthengi |
| 1 | Umthengisi oqeqeshiweyo we-peptide APIs evela eTshayina. |
| 2 | Imigca yemveliso eyi-16 enomthamo omkhulu owaneleyo wemveliso kunye nexabiso elikhuphisanayo |
| 3 | Imveliso iveliswa kwi-US FDA kunye ne-EDQM indawo evunyiweyo. |
A: Ewe, singapakisha njengemfuno yakho.
A: I-LC sight kunye ne-TT kwithuba lokuhlawula kwangaphambili elikhethwayo.
IMPENDULO: Ewe, nceda unikezele ngeenkcukacha zakho zomgangatho, siza kujonga kwi-R&D yethu kwaye sizame ukungqamanisa ubunjani bakho.
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