Ibakala leGMP iTeripressin acetate yenaliti
| Igama leGeneric: | I-Teripressin acetate |
| Inombolo yeCas: | 14636-12-5 |
| Ifomula yemolekyuli: | I-C52H74N16O15S2 |
| Ubunzima bemolekyuli: | 1227.39 g/mol |
| Ulandelelwano: | I-H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 ityuwa yeacetate(Disulfide bond) |
| Imbonakalo: | Umgubo omhlophe |
| Isicelo: | I-Terlipressin acetate yi-analog yokwenziwa kwe-vasopressin esetyenziselwa ikakhulu ukunyanga iimeko ezahlukeneyo, ezifana nokopha kwe-variceal esophageal, i-hepatorenal syndrome, kunye ne-septic shock.I-vasoconstrictor enamandla, oku kuthetha ukuba inceda ukuxinzelela imithambo yegazi kunye nokwandisa uxinzelelo lwegazi kwiindawo ezithile zomzimba.Eli chiza, elidla ngokunikezelwa ngenaliti, lisebenza kwii-receptors ezithile kwimithambo yegazi ukunciphisa ukuhamba kwegazi kwiindawo apho kufuneka khona, ngokunciphisa ukopha okanye ukuphucula uxinzelelo lwegazi.Idla ngokusetyenziswa kwiimeko ezingxamisekileyo, njengaxa isigulane esopha kakhulu ngenxa yee-varices ze-esophageal (imithambo yegazi eyongeziweyo kummizo).Enye yeenzuzo eziphambili ze-tervasopressin acetate lixesha elide lesenzo kunye nokukwazi ukuvelisa i-vasoconstriction eqhubekayo.Oku kunceda ukuzinzisa imeko yesigulane kwaye uthenge ixesha lokungenelela ngonyango olongezelelweyo.Nangona kunjalo, kubalulekile ukuqaphela ukuba i-tervasopressin acetate liyeza elimiselweyo kwaye kufuneka lisetyenziswe kuphela phantsi kolawulo kunye nesikhokelo sononophelo lwezempilo.Njengalo naliphi na iyeza, linokuba neziphumo ebezingalindelekanga, ezinje ngokuqaqanjelwa sisisu, isicaphucaphu, kunye notshintsho kwisantya sentliziyo kunye noxinzelelo lwegazi.Ngoko ke, kubalulekile ukuxoxa ngeengozi kunye neenzuzo zeli yeza kunye nochwepheshe bezonyango abaqeqeshiweyo ngaphambi kokuqala unyango.Ukuqukumbela, i-tervasopressin acetate lichiza elixabisekileyo kunyango lweemeko ezahlukeneyo zonyango ezinxulumene nokopha kunye nokulawulwa koxinzelelo lwegazi.Ukukwazi kwayo ukuxinzelela imithwalo yegazi kwenza kube sisixhobo esibalulekileyo kwiimeko ezingxamisekileyo apho kufuneka kwenziwe ngokukhawuleza.Nangona kunjalo, uhlolo olululo lwezonyango luyimfuneko ukuze kuqinisekiswe ukuba lusetyenziswa ngokukhuselekileyo nangempumelelo. |
| Umqulu: | ibhegi yefoyile ye-aluminiyam okanye i-TIN ye-aluminium okanye ngokweemfuno zomthengi |
| Umthamo wemveliso: | 2 Kilogram/Inyanga |
| 1 | Umthengisi oqeqeshiweyo we-peptide APIs evela eTshayina. |
| 2 | Imigca yemveliso eyi-16 enomthamo omkhulu owaneleyo wemveliso kunye nexabiso elikhuphisanayo |
| 3 | I-GMP kunye ne-DMF zifumaneka ngowona maxwebhu athembekileyo. |
A: Ewe, singapakisha njengemfuno yakho.
A: I-LC sight kunye ne-TT kwithuba lokuhlawula kwangaphambili elikhethwayo.
IMPENDULO: Ewe, nceda unikezele ngeenkcukacha zakho zomgangatho, siza kujonga kwi-R&D yethu kwaye sizame ukungqamanisa ubunjani bakho.
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