Tirzepatide
| Igama leGeneric: | Tirzepatide |
| Inombolo yeCas: | 2023788-19-2 |
| Ifomula yeemolekyuli: | C225H348N48O68 |
| Ubunzima bemolekyuli: | 4813.45 g/mol |
| Ulandelelwano: | H-Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-Ile-Ala-Gln-{diacid-gamma-Glu -(AEEA)2-Lys}-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| Imbonakalo: | Umgubo omhlophe |
| Isicelo: | I-Tirzepatide sisiyobisi esifundelwa ukusetyenziswa okunokubakho kunyango lwe-2 yeswekile. Kukwiklasi yeziyobisi ezibizwa ngokuba yi-diglucose-dependent insulinotropic peptide (GIP) kunye ne-glucagon-like peptide-1 (GLP-1) receptor agonists. I-Tezepatide isebenza ngokuvuselela i-GIP kunye ne-GLP-1 receptors emzimbeni. Ezi zamkeli zidlala indima ebalulekileyo ekulawuleni amanqanaba eswekile yegazi kunye ne-metabolism. Ngokusebenzisa ezi receptors, i-tezepatide yonyusa imveliso ye-insulin kwaye yehlisa ukukhutshwa kweglucagon, ihomoni ephakamisa amanqanaba eswekile yegazi. Ikwacothisa nokukhupha isisu kwaye inceda ukulawula amanqanaba eswekile yegazi. Ulingo lwezonyango lubonise ukuba i-tilsiparatide inokulawula ngokufanelekileyo amanqanaba eswekile yegazi kwizigulane ezinesifo seswekile se-2. Kwakhona kufunyenwe ukukhuthaza ukulahleka kwesisindo, okuyinzuzo eyongezelelweyo kubantu abaninzi abanesifo sikashukela sohlobo lwe-2 abanobunzima bokugcina ubunzima obunempilo. Enye yeenzuzo ze-tezeparatide yirejimeni yedosi yayo kanye ngeveki, enokuthi inyuse lula kunye nokuthotyelwa kwerejimeni yonyango. Oku kunokuba luncedo ngakumbi kubantu abanobunzima bokubambelela kwishedyuli yemihla ngemihla yamayeza okanye abakhetha isicwangciso sonyango esilungelelanisiweyo. Kufuneka kuqatshelwe ukuba i-tilsparatide isekwinqanaba lophando kwaye ayikavunywa ukuba isetyenziswe zii-arhente ezilawulayo. Uphando olongezelelweyo luyafuneka ukufumanisa ukhuseleko lwalo lwexesha elide kunye nokusebenza kunye nokuchonga nayiphi na imiphumo enokubakho. Isishwankathelo, i-tilsparatide lichiza elitsha eliphandwayo kunyango lwe-2 yeswekile. Isenzo salo esibini kwi-GIP kunye ne-GLP-1 i-receptors inamandla okuphucula ulawulo lwe-glycemic kunye nokulahlekelwa kwesisindo. Nangona kunjalo, uphando olongezelelweyo luyafuneka ngaphambi kokuba i-tilsiparatide inconywe njengendlela yonyango kubantu abanesifo seswekile se-2. |
| Umqulu: | ibhegi yefoyile ye-aluminiyam okanye i-TIN ye-aluminium okanye ngokweemfuno zomthengi |
| 1 | Umthengisi oqeqeshiweyo we-peptide APIs evela eTshayina. |
| 2 | Imigca yemveliso eyi-16 enomthamo omkhulu owaneleyo wemveliso kunye nexabiso elikhuphisanayo |
| 3 | I-DMF ifumaneka ngowona maxwebhu athembekileyo. |
A: Ewe, singapakisha njengemfuno yakho.
A: I-LC sight kunye ne-TT kwithuba lokuhlawula kwangaphambili elikhethwayo.
IMPENDULO: Ewe, nceda unikezele ngeenkcukacha zomgangatho wakho, siza kujonga kwi-R&D yethu kwaye sizame ukungqamanisa ubunjani bakho.
Bhala umyalezo wakho apha kwaye uwuthumele kuthi
