Ibakala leGMP iTirzepatide yokutofa
| Igama leGeneric: | Tirzepatide |
| Inombolo yeCas: | 2023788-19-2 |
| Ifomula yemolekyuli: | C225H348N48O68 |
| Ubunzima bemolekyuli: | 4813.45 g/mol |
| Ulandelelwano: | H-Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-Ile-Ala-Gln-{diacid-gamma-Glu -(AEEA)2-Lys}-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| Imbonakalo: | Umgubo omhlophe |
| Isicelo: | I-Tirzepatide sisiyobisi esifundelwa ukusetyenziswa okunokubakho kunyango lwe-2 yeswekile.Kukwiklasi yeziyobisi ezibizwa ngokuba yi-diglucose-dependent insulinotropic peptide (GIP) kunye ne-glucagon-like peptide-1 (GLP-1) receptor agonists.I-Tezepatide isebenza ngokuvuselela i-GIP kunye ne-GLP-1 receptors emzimbeni.Ezi zamkeli zidlala indima ebalulekileyo ekulawuleni amanqanaba eswekile yegazi kunye ne-metabolism.Ngokusebenzisa ezi receptors, i-tezepatide yonyusa imveliso ye-insulin kwaye yehlisa ukukhutshwa kweglucagon, ihomoni ephakamisa amanqanaba eswekile yegazi.Ikwacothisa nokukhupha isisu kwaye inceda ukulawula amanqanaba eswekile yegazi.Ulingo lwezonyango lubonise ukuba i-tilsiparatide inokulawula ngokufanelekileyo amanqanaba eswekile yegazi kwizigulane ezinesifo seswekile se-2.Kwakhona kufunyenwe ukukhuthaza ukulahleka kwesisindo, okuyinzuzo eyongezelelweyo kubantu abaninzi abanesifo sikashukela sohlobo lwe-2 abanobunzima bokugcina ubunzima obunempilo.Enye yeenzuzo ze-tezeparatide yirejimeni yedosi yayo kanye ngeveki, enokuthi inyuse lula kunye nokuthotyelwa kwerejimeni yonyango.Oku kunokuba luncedo ngakumbi kubantu abanobunzima bokubambelela kwishedyuli yemihla ngemihla yamayeza okanye abakhetha isicwangciso sonyango esilungelelanisiweyo.Kufuneka kuqatshelwe ukuba i-tilsparatide isekwinqanaba lophando kwaye ayikavunywa ukuba isetyenziswe zii-arhente ezilawulayo.Uphando olongezelelweyo luyafuneka ukufumanisa ukhuseleko lwalo lwexesha elide kunye nokusebenza kunye nokuchonga nayiphi na imiphumo enokubakho.Isishwankathelo, i-tilsparatide lichiza elitsha eliphandwayo kunyango lwe-2 yeswekile.Isenzo salo esibini kwi-GIP kunye ne-GLP-1 i-receptors inamandla okuphucula ulawulo lwe-glycemic kunye nokulahlekelwa kwesisindo.Nangona kunjalo, uphando olongezelelweyo luyafuneka ngaphambi kokuba i-tilsiparatide inconywe njengendlela yonyango kubantu abanesifo seswekile se-2. |
| Umqulu: | ibhegi yefoyile ye-aluminiyam okanye i-TIN ye-aluminium okanye ngokweemfuno zomthengi |
| 1 | Umthengisi oqeqeshiweyo we-peptide APIs evela eTshayina. |
| 2 | Imigca yemveliso eyi-16 enomthamo omkhulu owaneleyo wemveliso kunye nexabiso elikhuphisanayo |
| 3 | I-DMF ifumaneka ngowona maxwebhu athembekileyo. |
A: Ewe, singapakisha njengemfuno yakho.
A: I-LC sight kunye ne-TT kwithuba lokuhlawula kwangaphambili elikhethwayo.
IMPENDULO: Ewe, nceda unikezele ngeenkcukacha zakho zomgangatho, siza kujonga kwi-R&D yethu kwaye sizame ukungqamanisa ubunjani bakho.
Bhala umyalezo wakho apha kwaye uwuthumele kuthi
